Rejuran vs Profhilo vs Skinbooster: Which is Right for You?

Are your usual skincare products not as effective as before? Are you looking for extra skin hydration?

It may be time to go skin-deep through injectable moisturisers.

These are non-surgical injectables that cause deep skin hydration by delivering hyaluronic acid directly into the dermis.

In Singapore, you will find that you usually have Rejuran, Profhilo, and Skinboosters as your options for skin injectables — and for good reasons.

All of these are non-surgical, which means no need to go under the knife.

Their goals also overlap. Compared to dermal fillers, they do not change facial contours.

Instead, they improve common ageing skin concerns such as dry skin, fine lines, and skin laxity. 

With all these, how do you find the most suitable injectable moisturiser for your skin woes?

No worries!

We’ve created this Rejuran vs Skinboosters vs Profhilo guide just for you. Read on to know more.

What are skin injectables and, what makes them more effective than topical skincare products?

skin healing

To understand why injectable treatments are better at skin repair, we must first understand the role of collagen in our skin.

Collagen is a protein that provides structure to our bones, joints, and skin.

However, collagen production decreases as we age. With less collagen, our skin quality also decreases, resulting in skin dryness, skin laxity, and other ageing skin issues.

This is where injectable moisturisers come in.

Injectable moisturisers contain ingredients such as a mixed form of high and low-molecular-weight hyaluronic acid, polynucleotides, and amino acids that are necessary for collagen production.

They work by stimulating collagen synthesis and assisting in elastin and hyaluronic acid production for overall skin rejuvenation.

And because injectable moisturisers go directly into the dermis, they can work their magic from within, going where skincare products can’t penetrate.

Types of injectable moisturisers—Rejuran, Profhilo, and Skinboosters


rejuran healer requires many injection marks

Rejuran combines polynucleotides derived from salmon DNA, hyaluronic acid, and amino acids for collagen stimulation and skin repair. 

It comes in three different variants—Rejuran Healer, Rejuran Scar, and Rejuran I.

This injectable moisturiser is better suited for patients who have sensitive skin, age 20 years old and above.

Among its many benefits are the following:

  • repairs the skin barrier and promotes skin hydration
  • smoothens skin texture and uneven skin tone
  • minimises enlarged pores and depressed acne scars


Multiple manual micro-injections

Treatment regimen

3-4 sessions with one month between each session with a maintenance session every 6 months


About 2-3 days


Profhilo uses pure hyaluronic acid

Profhilo has a higher hyaluronic acid concentration than Rejuran and Skinboosters.

A stable mixed form of high and low-molecular-weight HA (hyaluronic acid) makes this injectable moisturiser a powerful biostimulator that can remodel skin tissue at several layers.

Profhilo is intended for individuals with sagging skin and who are looking to: 

  • improve fine lines, wrinkles, and acne scarring
  • minimise sagging skin from loss of skin elasticity  
  • rejuvenate and hydrate skin deeply from within


10 injection points using the Bio-Aesthetic Points technique

Treatment regimen

2 treatment sessions with one month in between and one session every 6-9 months as maintenance treatments


Profhilo has the least downtime among these injectable moisturisers—only taking 1-2 days


skin boosters target many injection points

Skinboosters increase the skin’s hydration levels through multiple micro injections of free hyaluronic acid injected under the dermis of the skin.

This injectable moisturiser is better suited for patients with dehydrated and dull skin who are looking to have plump, radiant, and youthful-looking skin and address the early signs of aging skin.  


Multiple manual micro-injections

Treatment regimen

3-4 sessions with one month in between each session; maintenance consists of 3 sessions about 2-4 weeks apart


About 3-5 days

Which injectable skin treatment is suitable for me? 

skin elasticity

No injectable moisturiser is better than one or the other; all three treatments come with their own set of benefits.

The best way to know is by identifying what your skin concerns are and your expectations of the treatment, including the number of injection points you need, maintenance and downtimes, and the costs.

As a general guide, however, choose Rejuran healer treatments are for acne scars, open pores, and sensitive skin, Profhilo injections for ageing skin that is plagued by dryness and laxity, and Skinboosters for deep skin hydration and glowing skin.

Cost of skin injectable treatments

profhilo vs rejuran costs

In Singapore, Profhilo runs between $1,000-$1,200 per 2ml syringe, while Rejuran costs around $900 per 2cc syringe for 2-3 syringes on the face and neck.

The price tag for Skinboosters is dependent on your provider and the brand they use.

Cienna can find the suitable treatment for your skin type and needs

profhilo vs rejuran vs skinboosters

Get deeper skin hydration and say goodbye to ageing skin issues with the right injectable moisturisers.

Our doctors at Cienna Aesthetics Medical Clinic are passionate not only about administering your treatment of choice but also about empowering you as you embark on your non-surgical aesthetic treatment journey.

They will walk you through from pre-consultation to post-treatment to make sure you are satisfied with your results.

Get a professional opinion on the suitable injectable treatment for your skincare needs. Request a consultation with our doctors today! 

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